Thio-ccPA, CAS [[779333-56-1]]

Product Overview

• Article Name: Thio-ccPA, CAS [[779333-56-1]]
• Biozol Catalog Number: ECH-L-7118-1MG
• Supplier Catalog Number: L-7118-1mg
• Alternative Catalog Number: ECH-L-7118-1MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Thio-ccPA is a stabilized analogue of carbacyclic phosphatidic acid (ccPA). It inhibits the lysoPLD activity of Autotaxin (ATX) and acts as an LPA1/3 receptor antagonist. Thio-ccPA decreases the viability of B16F10 A375 and MeWo melanoma cell lines. Addition of endogenous LPA did not reverse these effects in B16F10 cells. Thio-ccPA decreased the number of pulmonary and non-pulmonary metastases in a B16F10 metastatic melanoma mouse model.

Product Properties

• Tag: 742 743 443 744
• CAS Number: [779333-56-1]