XY-17 (LPA3 Agonist)
Catalog Number:
ECH-L-9118
Product Overview
Article Name:
XY-17 (LPA3 Agonist)
Biozol Catalog Number:
ECH-L-9118
Supplier Catalog Number:
L-9118
Alternative Catalog Number:
ECH-L-9118-500UG
Manufacturer:
Echelon Biosciences
Category:
Molekularbiologie
Product Description
XY-17 is a fluorinated phosphonate analog of lysophosphatidic acid (LPA). XY-17 is not hydrolyzed by lipid phosphate phosphatase (LPP) and acts as an agonist of the LPA3 receptor. Storage -20 C Alternate Name: (3S)-1-fluoro-3-hydroxy-4-butyl-1-phosphonate Featured in Publications 1) Xu, Y., M. Tanaka, et al. (2004). Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors. Bioorg Med Chem Lett 14(21): 5323-8. 2) Zhao, Y., P. V. Usatyuk, et al. (2005). Lipid phosphate phosphatase-1 regulates lysophosphatidic acid-induced calcium release, NF-kappaB activation and interleukin-8 secretion in human bronchial epithelial cells. Biochem. J. 385(2): 493-502. 3) Prestwich, G., Y. Xu, et al. (2005). New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors. Biochem Soc Trans 33: 1357-1361. 4) W.N. Ayre, T. Scott, et al. (2016) Fluorophosphonate-functionalised titanium via a pre-adsorbed alkane phosphonic acid: a novel dual action surface finish for bone regenerative applications. J Mater Sci Mater Med. Feb,27(2):36. doi: 10.1007/s10856-015-5644-7 Documents Technical Data Sheet
Application Notes
Application Notes:
Categories: Biochemical Reagents. Related: Agonist, Lysophosphatidic Acid. Ship 1 : Shipping Temp. Ship 2: Gel Ice
