93-O17S

Catalog Number: ECH-N-1175
Article Name: 93-O17S
Biozol Catalog Number: ECH-N-1175
Supplier Catalog Number: N-1175
Alternative Catalog Number: ECH-N-1175-100MG, ECH-N-1175-10MG, ECH-N-1175-25MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
93-O17S is a lipidoid used for generating lipid nanoparticles to deliver RNA, peptides, and nucleotides. 93-O17S LNPs were able to deliver Cre recombinase mRNA in mice. In addition, LNPs were able to deliver the Cre recombinase protein and Cas9: single-guide RNA into cells for genome editing. 93-O17S LNPs were used to deliver the STING pathway agonist 2′3′-Cyclic GMP-AMP (cGAMP) when injected into B16F10 tumors in mice which has potential as an in situ cancer vaccine.