GroPI

Product Overview

• Article Name: GroPI
• Biozol Catalog Number: ECH-P-0000
• Supplier Catalog Number: P-0000
• Alternative Catalog Number: ECH-P-0000-100UG,ECH-P-0000-1MG,ECH-P-0000-500UG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Glycerophosphoinositol (GroPI) is the building block for phosphoinositide polyphosphates and is a substrate for PI-PLC. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol (PI or PtdIns) is biosynthesized from CDP-diacylglycerol and inositol by phosphatidylinositol synthase. PI is the building block for phosphoinositide polyphosphates through phosphorylation by PI-kinases and is a substrate for PI-PLC yielding diacylgelycerol.

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Storage

-20 C

Featured in Publications

1) Zizza, P., C. Iurisci, et al. (2012). Phospholipase A2 IValpha regulates phagocytosis independent of its enzymatic activity. J Biol Chem 287(20): 16849-16859. 2) Vessichelli, M., et al. (2017). The natural phosphoinositide derivative glycerophosphoinositol inhibits the lipopolysaccharide-induced inflammatory and thrombotic responses. Journal of Biological Chemistry 292(31): 12828-12841. Bulk discounts available, please email echelon echelon-inc.com for information.

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Documents

Technical Data Sheet

Application Notes

• Application Notes: Categories: Lipids. Related: Glycerolphosphoinositide. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination