PI(5)P diC16
Catalog Number:
ECH-P-5016
Product Overview
Article Name:
PI(5)P diC16
Biozol Catalog Number:
ECH-P-5016
Supplier Catalog Number:
P-5016
Alternative Catalog Number:
ECH-P-5016-100UG,ECH-P-5016-1MG,ECH-P-5016-500UG
Manufacturer:
Echelon Biosciences
Category:
Molekularbiologie
Product Description
Phosphatidylinositol 5-phosphate diC16 (PI(5)P diC16) is a synthetic, purified dipalmitoyl PI(5)P. Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 5-phosphate (PI(5)P) is a rare lipid found in the nucleus that can bind the PHD finger of the nuclear adapter protein ING2. PI(5)P is phosphorylated to PI(4,5)P2 by Type II PIP kinases. Storage -20 C Featured in Publications 1) Barylko, B., S. H. Gerber, et al. (2001). A Novel Family of Phosphatidylinositol 4-Kinases Conserved from Yeast to Humans. J Biol Chem 276(11): 7705-7708. 2) Sbrissa, D., O. C. Ikonomov, et al. (2004). Role for a Novel Signaling Intermediate, Phosphatidylinositol 5-Phosphate, in Insulin-Regulated F-Actin Stress Fiber Breakdown and GLUT4 Translocation. Endocrinology 145(11): 4853-4865. 3) Grainger, D., C. Tavelis, et al. (2011). Involvement of phosphatidylinositol 5-phosphate in insulin-stimulated glucose uptake in the L6 myotube model of skeletal muscle. Pflugers Archiv European Journal of Physiology 462(5): 723-732. 4) Bua, D.J., Martin, G.M. et al. (2013). Nuclear phosphatidylinositol-5-phosphate regulates ING2 stability at discrete chromatin targets in response to DNA damage. Sci. Rep.3: 2137. 5) Sumita, K., Y.-H. Lo, et al. (2016). The Lipid Kinase PI5P4Kb Is an Intracellular GTP Sensor for Metabolism and Tumorigenesis. Molecular Cell. DOI:10.1016/j.molcel.2015.12.011 Alternate Names: D-myo-Phosphatidylinositol 5-phosphate, Dipalmitoyl Phosphatidylinositol 5-phosphate, PtdIns(5)P C16, PI(5)P C16, or PI5P Bulk discounts available, please email echelon echelon-inc.com for information. Documents Technical Data Sheet
Application Notes
Application Notes:
Categories: Lipids. Related: diC16, PI(5)P. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination
