PI4-Kinase II beta (PI4KIIb), active

Product Overview

• Article Name: PI4-Kinase II beta (PI4KIIb), active
• Biozol Catalog Number: ECH-P22-10G
• Supplier Catalog Number: P22-10G
• Alternative Catalog Number: ECH-P22-10G-10UG, ECH-P22-10G-5UG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Full-length recombinant human PI4KIIB was co-expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. Enzyme obtained from SignalChem. Molecular weight: ~84 kDa Sequence: Full length Species: Human Tag: GST tag Purity: >90 % (see TDS for lot specific information) Specific Activity: >30 nmol/min/mg (see TDS for lot specific information) Expression System: Sf9 insect cells using baculovirus Genebank Number: NM_018323 Applications: PI 4-Kinase assay , western blot. Formulation: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. Storage and stability: Store product at -70C. Stable up to one year

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Product Description: PI4KIIB is a member of the phosphatidylinositol 4-kinase family (PI4K) that phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate which are immediate precursor of several important signaling and scaffolding molecules. PI4KIIB is primarily a cytosolic PI4K that is recruited to membranes where it stimulates phosphatidylinositol 4,5-bisphosphate syntheses. PI4KIIB uses phosphatidylinositol as their primary substrate and has no activity on phosphatidylinositol monophosphates. PI4KIIB is a restricted minor histocompatibility antigen in patients that had been successfully treated with donor lymphocyte infusions for relapsed chronic myeloid leukemia after allogeneic stem cell transplantation.

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Application Notes

• Application Notes: Categories: Antibodies & Proteins. Related: Enzyme, Kinase, PI4K. Ship 1 : Shipping Temp. Ship 2: Dry Ice