**This product is being discontinued but stock is currently available.A Please call to place order: 801-588-0455**Membrane permeant inositol polyphosphates are employed in cell signaling experiments to introduce exogenous inositol polyphosphates across cell membranes. Some examples of applications are listed below. See the following page for an example protocol.1) M. Vajanaphanich et al. a€Long-term uncoupling of chloride secretion from intracellular calcium levels by Ins(3 4 5 6)P4a€ Nature 1994 971 711-714.2) M.T. Rudolf et al. a€A membrane-permeant bioactivatable derivative of Ins(1 3 4)P3 and its effect on Cl(-)-secretion from T84 cellsa€ Bioorg. Med. Chem.Lett. 1998 8 1857-1860.3) X. Yang et al. a€Inositol 1 3 4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3 4 5 6-tetrakisphosphate.a€ J. Biol. Chem. 1999 274 18973-18980.
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