S1P Fluorescein

Product Overview

• Article Name: S1P Fluorescein
• Biozol Catalog Number: ECH-S-200F
• Supplier Catalog Number: S-200F
• Alternative Catalog Number: ECH-S-200F-50UG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Echelon offers a unique selection of sphingosine 1-phosphate analogs labeled at the terminus of the alkyl chain with biotin or fluorescent groups. All compounds have the natural erythro stereochemistry and are synthesized from chiral precursors.

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Storage

Sphingosine 1-phosphate fluorescein (S1P fluorescein) is relatively stable at room temperature as a solid. It is best stored as a dried solid, protected from light at -20 C. Solutions/emulsions should be kept at -20 C. Storage in basic buffers (pH > 9.0) or acidic buffers (pH < 4.0) may cause decomposition.

Excitation/Emission

494/521 nm

Solubility

MeOH >1 mg/ml

Featured in Publications

1) Peest, U., S. C. Sensken, et al. (2008). S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake. J Cell Biochem 104(3): 756-72. 2) Meissner, A., J. Yang, et al. (2012). Tumor Necrosis Factor-alpha-Mediated Downregulation of the Cystic Fibrosis Transmembrane Conductance Regulator Drives Pathological Sphingosine-1-Phosphate Signaling in a Mouse Model of Heart Failure. Circulation 125(22): 2739-2750. 3) Vogt, K., et al. (2018). Release of Platelet-Derived Sphingosine-1-Phosphate Involves Multidrug Resistance Protein 4 (MRP4/ABCC4) and Is Inhibited by Statins. Thromb Haemost 118(01): 132-142. Bulk quantities of this product are available. Please email echelon echelon-inc.com for more information.

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Documents

Technical Data Sheet

Application Notes

• Application Notes: Categories: Lipids. Related: Fluorescent, Sphingolipid, Sphingosine 1-phosphate. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination