Sphingo Beads
Catalog Number:
ECH-S-6100
Product Overview
Article Name:
Sphingo Beads
Biozol Catalog Number:
ECH-S-6100
Supplier Catalog Number:
S-6100
Alternative Catalog Number:
ECH-S-6100-100UL,ECH-S-6100-1ML
Manufacturer:
Echelon Biosciences
Category:
Molekularbiologie
Product Description
Sphingo Beads are composed of agarose with 10 nanomoles of bound Sphingosine per mL of beads, enough for several protein binding experiments. Each 1 mL order includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase. Storage 4 C - do not freeze Applications Sphingo Beads are designed for use in protein pull-down experiments to identify and characterize sphingosine binding proteins. Possible applications include the isolation of lipid-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis. Featured in Publications 1) Alvarez, S. E., et al. (2010). Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2. Nature 465(7301): 1084. 2) Takasugi, N., et al. (2011). BACE1 activity is modulated by cell-associated sphingosine-1-phosphate. J Neurosci 31(18): 6850-6857 3) Parham, K. A., et al. (2015). Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-gamma that regulates neoangiogenesis. The FASEB Journal 29(9): 3638-3653. 4) Nair, S., et al. (2018). Antigen-mediated regulation in monoclonal gammopathies and myeloma. JCI insight 3(8) e98259. Being bio-reactive blog: Lipid-Ligand interaction tools: lipids are not scary intermediates anymore Documents Technical Data Sheet
Application Notes
Application Notes:
Categories: Biochemical Reagents. Related: Beads, Sphingolipid, Sphingosine. Ship 1 : Shipping Temp. Ship 2: Gel Ice
