S1P Beads

Catalog Number: ECH-S-6110
Article Name: S1P Beads
Biozol Catalog Number: ECH-S-6110
Supplier Catalog Number: S-6110
Alternative Catalog Number: ECH-S-6110-100UL, ECH-S-6110-1ML
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
S1P Beads are composed of agarose with 10 nanomoles of bound Sphingosine 1-Phosphate (S1P) per mL of beads, enough for several protein binding experiments. Each 1 mL order of S1P Beads includes a small amount of control beads. Larger quantities of Control Beads are also available for purchase.

Storage

4 C - do not freeze<

Applications

S1P beads are designed for use in protein pull-down experiments to identify and characterize S1P binding proteins. Possible applications include the isolation of lipid-binding proteins present in a cell lysate or in a mixture of in vitro translated peptides, for separation by SDS-PAGE and further analysis.

Featured in Publications

1)
N. C. Hait, J. Allegood, et al. (2009) Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate Science 325(5945), 1254-7 2) G. M. Strub, M. Paillard, et al. (2011) Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration The FASEB Journal 25(2), 600-612 10.1096/fj.10-167502 3) E.-S. Park, S. Choi, et al. (2015) Tumor Necrosis Factor (TNF) Receptor-associated Factor (TRAF)-interacting Protein (TRIP) Negatively Regulates the TRAF2 Ubiquitin-dependent Pathway by Suppressing the TRAF2-Sphingosine 1-Phosphate (S1P) Interaction J. Biol. Chem. 290(15), 9660-9673 10.1074/jbc.M114.609685 4) Parham, K. A., et al. (2015). Sphingosine 1-phosphate is a ligand for peroxisome proliferator-activated receptor-gamma that regulates neoangiogenesis. The FASEB Journal 29(9): 3638-3653. Being bio-reactive blog: Lipid-Ligand interaction tools: lipids are not scary intermediates anymore

Documents

Technical Data Sheet
Application Notes: Categories: Biochemical Reagents. Related: Beads, Sphingolipid, Sphingosine 1-phosphate. Ship 1 : Shipping Temp. Ship 2: Gel Ice