PI(3)P PolyPIPosomes
Catalog Number:
ECH-Y-P003
Product Overview
Article Name:
PI(3)P PolyPIPosomes
Biozol Catalog Number:
ECH-Y-P003
Supplier Catalog Number:
Y-P003
Alternative Catalog Number:
ECH-Y-P003-100UL,ECH-Y-P003-1ML,ECH-Y-P003-250UL
Manufacturer:
Echelon Biosciences
Category:
Molekularbiologie
Product Description
PolyPIPosomes are polymerized liposomes that show markedly increased stability (up to 6 months) vs. conventional liposomes. A biotin tag is incorporated for easy detection of PIPn-binding proteins with streptavidin reagents. - Uniform size (~200 nm) - Ready-to-use suspensions, no liposome preparation PolyPIPosomes have demonstrated utility in a number of assay formats: Protein pull-down Surface Plasmon Resonance Liposome overlay assay Control PolyPIPosomes. Featured in Publications 1) Ferguson, C. G., R. D. James, et al. (2005). Phosphoinositide-Containing Polymerized Liposomes: Stable Membrane-Mimetic Vesicles for Protein-Lipid Binding Analysis. Bioconjug Chem 16(6): 1475-1483. 2) Elkin, S. K., D. Ivanov, et al. (2005). A PHD finger motif in the C-terminus of RAG2 modulates recombination activity. J Biol Chem 280(31): 28701-10. 3) Mustafa, A. K., D. B. van Rossum, et al. (2009). Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition. Proc Natl Acad Sci U S A 106(8): 2921-6. 4) Zemskov, E. A., I. Mikhailenko, et al. (2011). Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomes. PLoS One 6(4): e19414. 5) Ueyama, T., J. Nakakita, et al. (2011). Cooperation of p40(phox) with p47(phox) for Nox2-based NADPH oxidase activation during Fcgamma receptor (FcgammaR)-mediated phagocytosis: mechanism for acquisition of p40(phox) phosphatidylinositol 3-phosphate (PI(3)P) binding. J Biol Chem 286(47): 40693-705. 6) Xhabija, B. and P. O. Vacratsis (2015). Receptor Mediated Endocytosis 8 Utilizes an N-terminal Phosphoinositide Binding Motif to Regulate Endosomal Clathrin Dynamics. The Journal of biological chemistry 290 21676-21689. Being bio-reactive blog: Lipid-Ligand interaction tools: lipids are not scary intermediates anymore Documents Technical Data Sheet
Application Notes
Application Notes:
Categories: Biochemical Reagents. Related: Phosphoinositides, PI(3)P, PolyPIPosomes. Ship 1 : Shipping Temp. Ship 2: Gel Ice
