PI(3,5)P2 PolyPIPosomes

Catalog Number: ECH-Y-P035
Article Name: PI(3,5)P2 PolyPIPosomes
Biozol Catalog Number: ECH-Y-P035
Supplier Catalog Number: Y-P035
Alternative Catalog Number: ECH-Y-P035-100UL,ECH-Y-P035-1ML,ECH-Y-P035-250UL
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
PolyPIPosomes are polymerized liposomes that show markedly increased stability (up to 6 months) vs. conventional liposomes. A biotin tag is incorporated for easy detection of PIPn-binding proteins with streptavidin reagents. - Uniform size (~200 nm) - Ready-to-use suspensions, no liposome preparation PolyPIPosomes have demonstrated utility in a number of assay formats: Protein pull-down Surface Plasmon Resonance Liposome overlay assay
PI(3,5)P2 PolyPIPosomes are provided as a 1mM total lipid solution containing 5% PI(3,5)P2. Each order of 250 µL or 1 mL of PolyPIPosomes includes 100 µL of Control PolyPIPosomes.

Featured in Publications

1)
Ferguson, C. G., R. D. James, et al. (2005). Phosphoinositide-Containing Polymerized Liposomes: Stable Membrane-Mimetic Vesicles for Protein-Lipid Binding Analysis. Bioconjug Chem 16(6): 1475-1483. 2) Elkin, S. K., D. Ivanov, et al. (2005). A PHD finger motif in the C-terminus of RAG2 modulates recombination activity. J Biol Chem 280(31): 28701-10. 3) Mustafa, A. K., D. B. van Rossum, et al. (2009). Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition. Proc Natl Acad Sci U S A 106(8): 2921-6. 4) Zemskov, E. A., I. Mikhailenko, et al. (2011). Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomes. PLoS One 6(4): e19414. 5) Hong, N. H., A. Qi, et al. (2015). PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions. J Cell Biology 210(5): 753-769. 6) Li, X., et al. (2013). Genetically encoded fluorescent probe to visualize intracellular phosphatidylinositol 3,5-bisphosphate localization and dynamics. Proc Natl Acad Sci U S A 110(52): 21165-21170. Being bio-reactive blog: Lipid-Ligand interaction tools: lipids are not scary intermediates anymore

Documents

Technical Data Sheet
Application Notes: Categories: Biochemical Reagents. Related: Phosphoinositides, PI(3\,5)P2, PolyPIPosomes. Ship 1 : Shipping Temp. Ship 2: Gel Ice