TMR-Anti-PI(4,5)P2

Product Overview

• Article Name: TMR-Anti-PI(4,5)P2
• Biozol Catalog Number: ECH-Z-R045
• Supplier Catalog Number: Z-R045
• Alternative Catalog Number: ECH-Z-R045-10UG, ECH-Z-R045-250UG, ECH-Z-R045-50UG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Purified Anti-PtdIns(4,5)P2 monoclonal antibody conjugated with Tetramethylrhodamine (TMR). Product Background: Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PIP3. This antibody clone is also available as purified, Fluorescein conjugated, and in ascites fluid.