MLKL (5E3) Mouse Monoclonal Antibody, IgG1, Unconjugated

Product Overview

• Article Name: MLKL (5E3) Mouse Monoclonal Antibody, IgG1, Unconjugated
• Biozol Catalog Number: EKL-AMM00761
• Supplier Catalog Number: AMM00761
• Alternative Catalog Number: EKL-AMM00761-50UL,EKL-AMM00761-100UL,EKL-AMM00761-500UL,EKL-AMM00761-200UL
• Manufacturer: EnkiLife
• Host: Mouse
• Category: Antikörper
• Application: IHC-P
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: MLKL

Product Description

Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Product Properties

• Clonality: Monoclonal
• Isotype: IgG1
• NCBI: 197259
• UniProt: Q8NB16
• Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Purity: Affinity Purification
• Form: Liquid
• Target: MLKL

Application Notes

• Application Dilute: IHC: 1:50-1:100