CD45 (8C1) Mouse Monoclonal Antibody, IgG1, Unconjugated

Catalog Number: EKL-AMM03711
Article Name: CD45 (8C1) Mouse Monoclonal Antibody, IgG1, Unconjugated
Biozol Catalog Number: EKL-AMM03711
Supplier Catalog Number: AMM03711
Alternative Catalog Number: EKL-AMM03711-50UL,EKL-AMM03711-100UL,EKL-AMM03711-500UL,EKL-AMM03711-200UL
Manufacturer: EnkiLife
Host: Mouse
Category: Antikörper
Application: ICC, IHC-Fr, IHC-P, WB
Species Reactivity: Human
Conjugation: Unconjugated
Alternative Names: GP180, L CA, CD45 antigen
Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.
Clonality: Monoclonal
Molecular Weight: Calculated MW: 145 kDa, Observed MW: 145 kDa
Isotype: IgG1
NCBI: 19264
UniProt: P06800
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purity: Affinity Purification
Form: Liquid
Target: Ptprc
Application Dilute: WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200