PI3 Kinase p85 alpha (1C8) Mouse Monoclonal Antibody, IgG1, Unconjugated

Product Overview

• Article Name: PI3 Kinase p85 alpha (1C8) Mouse Monoclonal Antibody, IgG1, Unconjugated
• Biozol Catalog Number: EKL-AMM03867
• Supplier Catalog Number: AMM03867
• Alternative Catalog Number: EKL-AMM03867-50UL, EKL-AMM03867-100UL, EKL-AMM03867-200UL
• Manufacturer: EnkiLife
• Host: Mouse
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: PIK3R1, GRB1, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha

Product Description

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: Calculated MW: 84 kDa, Observed MW: 84 kDa
• Isotype: IgG1
• NCBI: 5295
• UniProt: P27986
• Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Purity: Affinity Purification
• Form: Liquid
• Target: PIK3R1

Application Notes

• Application Dilute: WB 1:500-1:1000,IHC 1:50-1:100