UCHL1 / PGP9.5, UCHL1, B220, CD 45, CD45, cd45 antigen, ec3.1.3.48, GP 180, GP180, Human homolog of severe combined immunodeficiency due to PTPRC deficiency, L CA, L-CA, lca, Leukocyte common antigen, LY 5, LY5, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase receptor type c polypeptide, PTPRC, PTPRC_HUMAN, Receptor-type tyrosine-protein phosphatase C, SCID due to PTPRC deficiency, t200, T200 glycoprotein, T200 leukocyte common antigen.
PGP9.5 is a single chain transmembraneous glycoprotein which represents the low molecular weight isoform of the Leucocyte Common Antigen (LCA). Hydrolyze isopeptide bonds between the carboxy-terminal glycine of Ub and the epsilon-amino group of lysine on target proteins and involved in the cotranslational processing of pro-ubiquitin and ribosomal proteins translated as ubiquitin fusions.
