Phospholamban Rabbit Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: Phospholamban Rabbit Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMRE02437
• Supplier Catalog Number: AMRe02437
• Alternative Catalog Number: EKL-AMRE02437-50UL, EKL-AMRE02437-100UL, EKL-AMRE02437-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: IHC, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: PLN, PLB, Cardiac phospholamban, PLB

Product Description

Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.

Product Properties

• Clonality: Monoclonal
• Molecular Weight: Calculated MW: 6 kDa, Observed MW: 12,24 kDa
• NCBI: 5350
• UniProt: P26678
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Purity: Affinity Purification
• Form: Liquid
• Target: PLN

Application Notes

• Application Dilute: WB 1:500-1:1000,IHC 1:50-1:100,IP 1:20-1:50