SV40 T Antigen Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-AMRE03219
Supplier Catalog Number:
AMRe03219
Alternative Catalog Number:
EKL-AMRE03219-50UL, EKL-AMRE03219-100UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
ICC, IP, WB
Species Reactivity:
All
Conjugation:
Unconjugated
Alternative Names:
Large T antigen, LT, LT-AG
Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.