iNOS (12H16) Rabbit Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: iNOS (12H16) Rabbit Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMRE12619
• Supplier Catalog Number: AMRe12619
• Alternative Catalog Number: EKL-AMRE12619-50UL, EKL-AMRE12619-100UL, EKL-AMRE12619-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IP, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: HEP-NOS, Hepatocyte NOS, Inducible NO synthase, Inducible NOS, iNOS, NOS2,

Product Description

iNOS Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed:7531687, PubMed:7544004). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (By similarity). As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on Cys-247 implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (PubMed:25417112). Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8 (PubMed:19688109).

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 131kDa
• NCBI: 4843
• UniProt: P35228
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Purity: Affinity purification
• Form: Liquid
• Target: NOS2

Application Notes

• Application Dilute: WB 1:500-1:2000,ICC/IF 1:200-1:1500,IP 1:20-1:100