Placental Protein 14 / PAEP (11B8) Rabbit Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: Placental Protein 14 / PAEP (11B8) Rabbit Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMRE16236
• Supplier Catalog Number: AMRe16236
• Alternative Catalog Number: EKL-AMRE16236-50UL, EKL-AMRE16236-100UL, EKL-AMRE16236-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: GdA, GdF, GdS, Glycodelin A, Glycodelin, Glycodelin F, Glycodelin S, PAEG, PAEP, PEG, PEP, Placental protein 14, PP14,

Product Description

This protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:9918684, PubMed:7531163). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155).

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 21kDa
• NCBI: 5047
• UniProt: P09466
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Purity: Affinity purification
• Form: Liquid
• Target: PAEP

Application Notes

• Application Dilute: WB 1:1000-1:5000