pro Caspase 7 (10O2) Rabbit Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: pro Caspase 7 (10O2) Rabbit Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMRE16509
• Supplier Catalog Number: AMRe16509
• Alternative Catalog Number: EKL-AMRE16509-50UL, EKL-AMRE16509-100UL, EKL-AMRE16509-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IHC, WB
• Species Reactivity: Human
• Conjugation: Unconjugated
• Alternative Names: apoptosis-related cysteine peptidase, Apoptotic protease Mch-3, CASP-7, Caspase-7 subunit p11, CMH-1, ICE-LAP3, ICE-like apoptotic protease 3,

Product Description

Belongs to the peptidase C14A family. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp--Gly-217 bond. Overexpression promotes programmed cell death. Involved in the activation cascade of caspases responsible for apoptosis execution (PubMed:8521391, PubMed:8576161, PubMed:8567622, PubMed:9070923, PubMed:11701129). Cleaves and activates sterol regulatory element binding proteins (SREBPs) (PubMed:8521391, PubMed:8576161, PubMed:8567622, PubMed:9070923). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a 216-Asp-|-Gly-217 bond. Overexpression promotes programmed cell death (PubMed:8521391, PubMed:8576161, PubMed:8567622, PubMed:9070923). Cleaves phospholipid scramblase proteins XKR4, XKR8 and XKR9 (By similarity).

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 34kDa
• NCBI: 840
• UniProt: P55210
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Purity: Affinity purification
• Form: Liquid
• Target: CASP7

Application Notes

• Application Dilute: WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200