Rab4A (17S4) Rabbit Monoclonal Antibody, Unconjugated

Product Overview

• Article Name: Rab4A (17S4) Rabbit Monoclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-AMRE16793
• Supplier Catalog Number: AMRe16793
• Alternative Catalog Number: EKL-AMRE16793-50UL, EKL-AMRE16793-100UL, EKL-AMRE16793-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: ICC, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: Rab4, RAB4A, HRES 1, RAB4, Ras related protein Rab 4A,

Product Description

The protein encoded by this gene belongs to the rab family. Rab4A protein is involved in the regulation of procathepsin L secretion, it was either inhibited by expression of a Rab4A dominant-negative mutant or increased by overexpression of the wild-type Rab4A in human melanoma cells. Small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state (PubMed:15907487, PubMed:16034420). Involved in protein transport (PubMed:29425100). Plays a role in vesicular traffic. Mediates VEGFR2 endosomal trafficking to enhance VEGFR2 signaling (PubMed:29425100). Acts as a regulator of platelet alpha- granule release during activation and aggregation of platelets (By similarity).

Product Properties

• Clonality: Monoclonal
• Molecular Weight: 24kDa
• NCBI: 5867
• UniProt: P20338
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4C short term. Store at -20C long term. Avoid freeze / thaw cycle.
• Purity: Affinity purification
• Form: Liquid
• Target: RAB4A

Application Notes

• Application Dilute: WB 1:1000-1:5000,ICC/IF 1:100-1:200