Acetyl-Coenzyme A Carboxylase Rabbit Monoclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-AMRE86998
Supplier Catalog Number:
AMRe86998
Alternative Catalog Number:
EKL-AMRE86998-50UL,EKL-AMRE86998-100UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
FC, ICC, IHC, WB
Species Reactivity:
Human
Conjugation:
Unconjugated
Alternative Names:
ACC, ACAC, ACC1, ACCA, ACACAD
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5 sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
