Axin 2 Rabbit Polyclonal Antibody, Unconjugated

Product Overview

• Article Name: Axin 2 Rabbit Polyclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-APRAB00181
• Supplier Catalog Number: APRab00181
• Alternative Catalog Number: EKL-APRAB00181-20UL, EKL-APRAB00181-50UL, EKL-APRAB00181-100UL, EKL-APRAB00181-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: ICC, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: Axil, Axin like protein, Axin2, Axis inhibition protein 2, Conductin

Product Description

Axin1 (Axis inhibition protein 1) and Axin2 are multidomain scaffold proteins that negatively regulate Wnt signaling. Axin1 interacts with APC, GSK-3beta, Dvl, and beta-catenin and promotes the GSK-3beta-mediated phosphorylation and subsequent degradation of beta-catenin .Down-regulates beta-catenin.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: Calculated MW: 94 kDa, Observed MW: 94 kDa
• NCBI: 8313
• UniProt: Q9Y2T1
• Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Purity: Affinity Chromatography
• Form: Liquid
• Target: AXIN2

Application Notes

• Application Dilute: WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200