FADD Rabbit Polyclonal Antibody, Unconjugated
Catalog Number:
EKL-APRAB00259
Product Overview
Article Name:
FADD Rabbit Polyclonal Antibody, Unconjugated
Biozol Catalog Number:
EKL-APRAB00259
Supplier Catalog Number:
APRab00259
Alternative Catalog Number:
EKL-APRAB00259-20UL, EKL-APRAB00259-50UL, EKL-APRAB00259-100UL, EKL-APRAB00259-200UL
Manufacturer:
EnkiLife
Host:
Rabbit
Category:
Antikörper
Application:
FC, IHC, WB
Species Reactivity:
Mouse
Conjugation:
Unconjugated
Alternative Names:
FADD protein, GIG3, Growth inhibiting gene 3 protein, Mediator of receptor induced toxicity, MORT1
Product Description
Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
Product Properties
Clonality:
Polyclonal
Molecular Weight:
Calculated MW: 23 kDa, Observed MW: 28 kDa
NCBI:
14082
UniProt:
Q61160
Buffer:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity:
Affinity Chromatography
Form:
Liquid
Target:
Fadd
Application Notes
Application Dilute:
WB 1:500-1:1000,IHC 1:50-1:100,FC 1:50-1:100
