Phospho-IKK alpha/beta (Ser176/Ser177) Rabbit Polyclonal Antibody, Unconjugated

Product Overview

• Article Name: Phospho-IKK alpha/beta (Ser176/Ser177) Rabbit Polyclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-APRAB00934
• Supplier Catalog Number: APRab00934
• Alternative Catalog Number: EKL-APRAB00934-20UL, EKL-APRAB00934-50UL, EKL-APRAB00934-100UL, EKL-APRAB00934-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: WB
• Species Reactivity: Human, Mouse, Rat
• Conjugation: Unconjugated
• Alternative Names: CHUK, IKKA, TCF16, Inhibitor of nuclear factor kappa-B kinase subunit alpha, I-kappa-B kinase alpha, IKK-A, IKK-alpha, IkBKA, IkappaB kinase, Conserved helix-loop-helix ubiquitous kinase, I-kappa-B kinase 1, IKK1, Nuclear factor NF-kappa-B

Product Description

Plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Activation of IKK depends upon phosphorylation at Ser177 and Ser181 in the activation loop of IKKbeta (Ser176 and Ser180 in IKKalpha), which causes conformational changes, resulting in kinase activation.

Product Properties

• Clonality: Polyclonal
• Molecular Weight: Calculated MW: 85 kDa, Observed MW: 85 kDa
• NCBI: 1147
• UniProt: O15111
• Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Purity: Affinity Purification
• Form: Liquid
• Target: CHUK

Application Notes

• Application Dilute: WB 1:500-1:1000