LEF1 Rabbit Polyclonal Antibody, Unconjugated

Product Overview

• Article Name: LEF1 Rabbit Polyclonal Antibody, Unconjugated
• Biozol Catalog Number: EKL-APRAB01396
• Supplier Catalog Number: APRab01396
• Alternative Catalog Number: EKL-APRAB01396-20UL, EKL-APRAB01396-50UL, EKL-APRAB01396-100UL, EKL-APRAB01396-200UL
• Manufacturer: EnkiLife
• Host: Rabbit
• Category: Antikörper
• Application: FC, ICC, IHC, IP, WB
• Species Reactivity: Human, Rat
• Conjugation: Unconjugated
• Alternative Names: LEF1, Lymphoid enhancer-binding factor 1, LEF-1, T cell-specific transcription factor 1-alpha, TCF1-alpha

Product Description

Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).

Product Properties

• Clonality: Polyclonal
• Molecular Weight: Calculated MW: 44 kDa, Observed MW: 25-58 kDa
• NCBI: 51176
• UniProt: Q9UJU2
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Purity: Affinity Purification
• Form: Liquid
• Target: LEF1

Application Notes

• Application Dilute: WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:50-1:100,IP 1:20-1:50