Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody, Unconjugated

Catalog Number: EKL-APRAB03382
Article Name: Phospho-Chk2 (Thr68) Rabbit Polyclonal Antibody, Unconjugated
Biozol Catalog Number: EKL-APRAB03382
Supplier Catalog Number: APRab03382
Alternative Catalog Number: EKL-APRAB03382-20UL, EKL-APRAB03382-50UL, EKL-APRAB03382-100UL, EKL-APRAB03382-200UL
Manufacturer: EnkiLife
Host: Rabbit
Category: Antikörper
Application: ICC, IHC, WB
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Alternative Names: CHEK2, CDS1, CHK2, RAD53, Serine/threonine-protein kinase Chk2, CHK2 checkpoint homolog, Cds1 homolog, Hucds1, hCds1, Checkpoint kinase 2
These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function.
Clonality: Polyclonal
Molecular Weight: Calculated MW: 61 kDa, Observed MW: 61 kDa
NCBI: 11200
UniProt: O96017
Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purity: Affinity Purification
Form: Liquid
Target: CHEK2
Application Dilute: WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200