Members of the precerebellin family, such as CBLN3, contain a cerebellin motif (see CBLN1, MIM 600432) and a C-terminal C1q signature domain (see MIM 120550) that mediates trimeric assembly of atypical collagen complexes. However, precerebellins do not contain a collagen motif, suggesting that they are not conventional components of the extracellular matrix (Pang et al., 2000 [PubMed 10964938]).[supplied by OMIM, Aug 2009],function:May be involved in synaptic functions in the CNS.,similarity:Contains 1 C1q domain.,subcellular location:Secretion depends probably on a association with CBLN1 or perhaps CBLN4 but not on CBLN2.,subunit:Heterohexamer, disulfide-linked heterotrimers. Does not homooligomerize, but probably forms a complex with at least CBLN1. May interact with CBLN2 and CBLN4.,
