CHD1L, ALC1, Chromodomain-helicase-DNA-binding protein 1-like, Amplified in liver cancer protein 1
chromodomain helicase DNA binding protein 1 like(CHD1L) Homo sapiens This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Several alternatively spliced transcripts variants have been described for this gene. [provided by RefSeq, Jan 2012],function:Putative DNA helicase, which may play a role in chromatin-remodeling. In vitro, promotes cell proliferation and inhibits apoptois.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,similarity:Contains 1 Macro domain.,tissue specificity:Frequently overexpresssed in hepatomacellular carcinomas.,
