THOC5, C22orf19, KIAA0983, THO complex subunit 5 homolog, Functional spliceosome-associated protein 79, fSAP79, NF2/meningioma region protein pK1.3, Placental protein 39.2, PP39.2, hTREX90
function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R, which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,function:May be involved in the differentiation of granulocytes and adipocytes.,PTM:Phosphorylated on tyrosine upon binding to activated CSF1R, which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity). Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the THOC5 family.,subcellular location:Shuttles between nucleus and cytoplasm.,subunit:Interacts with phosphorylated CSF1R.,tissue specificity:Ubiquitously expressed.,
