GNRH1, GNRH, GRH, LHRH, Progonadoliberin-1, Progonadoliberin I
gonadotropin releasing hormone 1(GNRH1) Homo sapiens This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015],function:Stimulates the secretion of gonadotropins, it stimulates the secretion of both luteinizing and follicle-stimulating hormones.,online information:Gonadotropin-releasing hormone entry,pharmaceutical:Available under the names Factrel (Ayerst Labs), Lutrepulse or Lutrelef (Ferring Pharmaceuticals) and Relisorm (Serono). Used in evaluating hypothalamic-pituitary gonadotropic function.,similarity:Belongs to the GnRH family.,
