HOXB1, HOX2I, Homeobox protein Hox-B1, Homeobox protein Hox-2I, HOXA1, HOX1F, Homeobox protein Hox-A1, Homeobox protein Hox-1F, HOXD1, HOX4, HOX4G, Homeobox protein Hox-D1, Homeobox protein Hox-GG
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008],function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.,polymorphism:The two common alleles, HOX1B*A and HOX1B*B have a frequency of 78.8% and 21.2% respectively.,similarity:Belongs to the Antp homeobox family. Labial subfamily.,similarity:Contains 1 homeobox DNA-binding domain.,
