This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2013],catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The [NKR]KIAxRE motif seems to be a cyclin-binding region.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.,similarity:Contains 1 protein kinase domain.,tissue specificity:Highly expressed in kidney, and to a lower extent in ovary.,
