The protein encoded by this gene is a membrane-bound receptor and member of the melanocortin receptor family. The encoded protein interacts with adrenocorticotropic and MSH hormones and is mediated by G proteins. This is an intronless gene. Defects in this gene are a cause of autosomal dominant obesity. [provided by RefSeq, Jan 2010],disease:Defects in MC4R are a cause of autosomal dominant obesity [MIM:601665].,function:Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase.,online information:Melanocortin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with ATRNL1.,tissue specificity:Brain, placental, and gut tissues.,
