This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly. [provided by RefSeq, Oct 2012],sequence caution:Translated as stop.,sequence caution:Translation N-terminally extended.,similarity:Contains 2 WD repeats.,tissue specificity:Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small inntestine and thymus. Up-regulated together with N-myc in some neuroblastoma cell lines.,
