NKX6-1, NKX6A, Homeobox protein Nkx-6.1, Homeobox protein NK-6 homolog A
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008],function:May be important for control of islet development and/or regulation of insulin biosynthesis.,similarity:Contains 1 homeobox DNA-binding domain.,tissue specificity:Pancreatic beta cells.,