SLC25A11, SLC20A4, Mitochondrial 2-oxoglutarate/malate carrier protein, OGCP, Solute carrier family 25 member 11
The oxoglutarate/malate carrier transports 2-oxoglutarate across the inner membranes of mitochondria in an electroneutral exchange for malate or other dicarboxylic acids (summary by Iacobazzi et al., 1992 [PubMed 1457818]).[supplied by OMIM, Jan 2011],function:Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism.,similarity:Belongs to the mitochondrial carrier family.,similarity:Contains 3 Solcar repeats.,
