RASSF4, AD037, Ras association domain-containing protein 4
The function of this gene has not yet been determined but may involve a role in tumor suppression. Alternative splicing of this gene results in several transcript variants, however, most of the variants have not been fully described. [provided by RefSeq, Jul 2008],function:Potential tumor suppressor. May act as a KRAS effector protein. May promote apoptosis and cell cycle arrest.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 SARAH domain.,subunit:Interacts directly with activated KRAS in a GTP-dependent manner.,tissue specificity:Widely expressed. Frequently down-regulated in tumor cell lines.,
