The protein encoded by this gene is secreted, likely interacting with roundabout homolog receptors to effect cell migration. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012],function:May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.,sequence caution:Intron retention.,similarity:Contains 1 CTCK (C-terminal cystine knot-like) domain.,similarity:Contains 1 laminin G-like domain.,similarity:Contains 23 LRR (leucine-rich) repeats.,similarity:Contains 9 EGF-like domains.,tissue specificity:Predominantly expressed in thyroid.,
