Aldo-Keto Reductase Family 1 Member C2, 3-Alpha-HSD3, Chlordecone Reductase Homolog HAKRD, Dihydrodiol Dehydrogenase 2, DD-2, DD2, Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein, DD/BABP, Trans-1, 2-Dihydrobenzene-1, 2-Diol Dehydrogenase, Type III 3-Alpha-Hydroxysteroid Dehydrogenase, AKR1C2, DDH2
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-alpha/5-beta-Steroid Reductases to convert Steroid hormones into the 3-alpha/5-alpha and 3-alpha/5-beta-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-alpha-Dihydrotestosterone (5-alpha-DHT) to 5-alpha-Androstane-3-alpha, 17-beta-diol (3-alpha-diol).
