Recombinant Human BCAS2 (C-6His, N-T7 tag), E. coli

Catalog Number: EKL-PEH0136
Article Name: Recombinant Human BCAS2 (C-6His, N-T7 tag), E. coli
Biozol Catalog Number: EKL-PEH0136
Supplier Catalog Number: PEH0136
Alternative Catalog Number: EKL-PEH0136-10UG,EKL-PEH0136-50UG,EKL-PEH0136-500UG
Manufacturer: EnkiLife
Host: E. coli
Category: Proteine/Peptide
Species Reactivity: Human
Alternative Names: Pre-mRNA-Splicing Factor SPF27, Breast Carcinoma-Amplified Sequence 2, DNA Amplified in Mammary Carcinoma 1 Protein, Spliceosome-Associated Protein SPF 27, BCAS2, DAM1
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.
Molecular Weight: 28.58 KDa
NCBI: 75934
Purity: Greater than 95% as determined by reducing SDS-PAGE
Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.