Recombinant Human GADD45B (N-6His), E. coli

Product Overview

• Article Name: Recombinant Human GADD45B (N-6His), E. coli
• Biozol Catalog Number: EKL-PEH0698
• Supplier Catalog Number: PEH0698
• Alternative Catalog Number: EKL-PEH0698-10UG,EKL-PEH0698-50UG,EKL-PEH0698-500UG
• Manufacturer: EnkiLife
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Growth Arrest and DNA Damage-Inducible Protein GADD45 Beta, Myeloid Differentiation Primary Response Protein MyD118, Negative Growth Regulatory Protein MyD118, GADD45B, MYD118

Product Description

Growth Arrest and DNA Damage-Inducible Protein GADD45 beta (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of growth and apoptosis. GADD45B reacts to environmental stresses by mediating activation of stress-responsive MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. In addition, GADD45B participates in the down-regulation of hepatocellular carcinoma (HCC). It may serve as a possible therapeutic target.

Product Properties

• Molecular Weight: 20 KDa
• NCBI: 75293
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.