Recombinant Human OBFc1 (N-6His), E. coli

Product Overview

• Article Name: Recombinant Human OBFc1 (N-6His), E. coli
• Biozol Catalog Number: EKL-PEH1575
• Supplier Catalog Number: PEH1575
• Alternative Catalog Number: EKL-PEH1575-10UG,EKL-PEH1575-50UG,EKL-PEH1575-500UG
• Manufacturer: EnkiLife
• Host: E. coli
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: CST Complex Subunit STN1, Oligonucleotide/Oligosaccharide-Binding Fold-Containing Protein 1, Suppressor of Cdc Thirteen Homolog, OBFC1, STN1

Product Description

CST Complex Subunit STN1 (OBFC1) is a 368 amino acid protein that contains one OB DNA-binding domain. It is a member of the STN1 family. OBFC1 is component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.

Product Properties

• Molecular Weight: 44.3 KDa
• NCBI: 17400
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.