Recombinant Human ANTXR1 (C-6His)

Product Overview

• Article Name: Recombinant Human ANTXR1 (C-6His)
• Biozol Catalog Number: EKL-PHH0077
• Supplier Catalog Number: PHH0077
• Alternative Catalog Number: EKL-PHH0077-10UG,EKL-PHH0077-50UG,EKL-PHH0077-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Anthrax Toxin Receptor 1, Tumor Endothelial Marker 8, ANTXR1, ATR, TEM8

Product Description

Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI).

Product Properties

• Molecular Weight: 33.56 KDa
• NCBI: 9
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.