Recombinant Human BMPR1A (C-Fc-6His)

Product Overview

• Article Name: Recombinant Human BMPR1A (C-Fc-6His)
• Biozol Catalog Number: EKL-PHH0160
• Supplier Catalog Number: PHH0160
• Alternative Catalog Number: EKL-PHH0160-10UG,EKL-PHH0160-50UG,EKL-PHH0160-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: Bone Morphogenetic Protein Receptor Type-1A, BMP Type-1A Receptor, BMPR-1A, Activin Receptor-Like Kinase 3, ALK-3, Serine/Threonine-Protein Kinase Receptor R5, SKR5, CD292, BMPR1A, ACVRLK3, ALK3

Product Description

Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, binding with ligands. Defects in BMPR1A are a cause of juvenile polyposis syndrome, Cowden disease and hereditary mixed polyposis syndrome 2 (HMPS2).

Product Properties

• Molecular Weight: 42.1 KDa
• NCBI: 36894
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.