Recombinant Human CCL8 (C-6His)

Product Overview

• Article Name: Recombinant Human CCL8 (C-6His)
• Biozol Catalog Number: EKL-PHH0274
• Supplier Catalog Number: PHH0274
• Alternative Catalog Number: EKL-PHH0274-10UG,EKL-PHH0274-50UG,EKL-PHH0274-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: C-C Motif Chemokine 8, HC14, Monocyte Chemoattractant Protein 2, Monocyte Chemotactic Protein 2, MCP-2, Small-Inducible Cytokine A8, CCL8, MCP2, SCYA10, SCYA8

Product Description

Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.

Product Properties

• Molecular Weight: 9.95 KDa
• NCBI: 26243
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.