Recombinant Human VCAM-1 (C-6His)

Catalog Number: EKL-PHH0279
Article Name: Recombinant Human VCAM-1 (C-6His)
Biozol Catalog Number: EKL-PHH0279
Supplier Catalog Number: PHH0279
Alternative Catalog Number: EKL-PHH0279-10UG,EKL-PHH0279-50UG,EKL-PHH0279-500UG
Manufacturer: EnkiLife
Host: Human
Category: Proteine/Peptide
Species Reactivity: Human
Alternative Names: Vascular Cell Adhesion Protein 1, V-CAM 1, VCAM-1, INCAM-100, CD106, VCAM1, L1CAM
VCAM-1 is a single-pass type I membrane protein, contains 7 Ig-like C2-type domains. It is an endothelial ligand for very late antigen-4 (VLA-4) and alpha4ß7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is induced on endothelial cells during inflammatory bowel disease, atherosclerosis, allograft rejection, infection, and asthmatic responses. During these responses, VCAM-1 forms a scaffold for leukocyte migration. VCAM-1 also activates signals within endothelial cells resulting in the opening of an //
Molecular Weight: 75.26 KDa
NCBI: 19320
Purity: Greater than 95% as determined by reducing SDS-PAGE
Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.