Recombinant Human CD3E (C-6His)

Product Overview

• Article Name: Recombinant Human CD3E (C-6His)
• Biozol Catalog Number: EKL-PHH0344
• Supplier Catalog Number: PHH0344
• Alternative Catalog Number: EKL-PHH0344-10UG,EKL-PHH0344-50UG,EKL-PHH0344-500UG
• Manufacturer: EnkiLife
• Host: Human
• Category: Proteine/Peptide
• Species Reactivity: Human
• Alternative Names: T-Cell Surface Glycoprotein CD3 Epsilon Chain, T-Cell Surface Antigen T3/Leu-4 Epsilon Chain, CD3e, CD3E, T3E

Product Description

T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3epsilon) is a single-pass type I membrane protein. CD3epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.

Product Properties

• Molecular Weight: 12.79 KDa
• NCBI: 07766
• Purity: Greater than 95% as determined by reducing SDS-PAGE

Application Notes

• Application Notes: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100µg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.